# Why pushing sensitivity of assays

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Normal assays for biomolecules have detection thresholds of around $$pM$$. However, a tumor of $$1mm^3$$ contains around 1 million cells. Each secrete around 5000 proteins, and the human body has around 5 liters of blood. This gives around $$10^6 \frac{\textrm{prot}}{ml}$$, or $$2\cdot10^{-15}$$