how to extract ev's from blood plasma

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The process for extracting EV's from blood plasma is not straightforward. However, the core principle relies on size exclusion chromatography: blood plasma is centrifuged twice to remove platelets, and stored at -80. When needed, it is divided through a SEC column (technical term: eluted, resulting samples are eluates).1.

  1. Journal of Thrombosis and Haemostasis, 16, 1423-1436 (Libregts, ..., E.N.M. Nolte-'T Hoen, ...) 

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